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106 results

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Page 1
Cycloartane triterpenoids from Pseudolarix amabilis and their antiviral activity.
Zhao XT, Yu MH, Su SY, Shi XL, Lei C, Hou AJ. Zhao XT, et al. Phytochemistry. 2020 Mar;171:112229. doi: 10.1016/j.phytochem.2019.112229. Epub 2020 Jan 1. Phytochemistry. 2020. PMID: 31901474
Seven undescribed cycloartane triterpenoids, pseudolarnoids A-G, together with ten known ones, were isolated from the seeds of Pseudolarix amabilis (J. Nelson) Rehder. Their structures were elucidated on the basis of spectroscopic analysis, X-ray crystallography, and ECD d …
Seven undescribed cycloartane triterpenoids, pseudolarnoids A-G, together with ten known ones, were isolated from the seeds of Pseudolari …
[Diterpenoid constituents in Pseudolarix amabilis and their antitumor activities in vitro].
Wang SY, Zhu YX, Zhang ZX, Yang CS, Xia HM, Su GZ, Li Y. Wang SY, et al. Zhongguo Zhong Yao Za Zhi. 2023 Jan;48(1):96-104. doi: 10.19540/j.cnki.cjcmm.20220427.201. Zhongguo Zhong Yao Za Zhi. 2023. PMID: 36725262 Chinese.
By various chromatographic techniques and extensive spectroscopic methods, 17 abietane diterpenoids were isolated from the dichloromethane fraction of the 95% ethanol cold-soak extracts of the seeds of Pseudolarix amabilis, namely pseudoamaol A(1), 12alpha-hydroxyabietic a …
By various chromatographic techniques and extensive spectroscopic methods, 17 abietane diterpenoids were isolated from the dichloromethane f …
Pseudoamaolides A-O, anti-inflammatory triterpene spiroketal lactones from seeds of Pseudolarix amabilis.
Zhu Y, Wang S, Zhang Z, Zhang H, Chai L, Liu G, Yang C, Zhang H, Wu L, Li Y. Zhu Y, et al. Bioorg Chem. 2022 Dec;129:106180. doi: 10.1016/j.bioorg.2022.106180. Epub 2022 Sep 29. Bioorg Chem. 2022. PMID: 36208500
Fifteen new triterpenoids (1-15), along with twenty known ones (16-35), were isolated from Pseudolarix amabilis. The triterpenoid structures include multiple skeleton types, such as 2,3-seco-cycloartane, 3,4-seco-cycloartane, 3,4:9,10-diseco-cycloartane, and 3,4:8,9:9,10-t …
Fifteen new triterpenoids (1-15), along with twenty known ones (16-35), were isolated from Pseudolarix amabilis. The triterpenoid str …
Chemical constituents from Pseudolarix kaempferi.
Yang SP, Wang Y, Wu Y, Yue JM. Yang SP, et al. Nat Prod Res. 2004 Oct;18(5):439-46. doi: 10.1080/14786410310001643911. Nat Prod Res. 2004. PMID: 15248612
A novel degraded triterpenoid isopseudolaritone A (1) and one new oligosaccharide, 1-O-isopropyl-6-O-[2-O-methyl-alpha-L-rhamnopyranosyl(1 --> 6)]-beta-D-glucopyranose (2), two new artefacts, 9-O-formacyl cedrusin (5) and 9,9'-O-diformacyl cedrusin (6), as well as 12 known phe …
A novel degraded triterpenoid isopseudolaritone A (1) and one new oligosaccharide, 1-O-isopropyl-6-O-[2-O-methyl-alpha-L-rhamnopyranosyl(1 - …
New triterpenoids and PTP1B inhibitory constituents of Pseudolarix amabilis.
Lei C, Huang QH, Zhao T, Wang PP, Li JY, Li J, Hou AJ. Lei C, et al. Fitoterapia. 2019 Nov;139:104414. doi: 10.1016/j.fitote.2019.104414. Epub 2019 Nov 6. Fitoterapia. 2019. PMID: 31705950
Six new triterpenoids, pseudolarins A-F (1-6), were isolated from the twigs of Pseudolarix amabilis, together with four known triterpenoids (7-10) and five known diterpenoids (11-15). ...
Six new triterpenoids, pseudolarins A-F (1-6), were isolated from the twigs of Pseudolarix amabilis, together with four known triterp …
Pseudolarix acid B inhibits angiogenesis by antagonizing the vascular endothelial growth factor-mediated anti-apoptotic effect.
Tan WF, Zhang XW, Li MH, Yue JM, Chen Y, Lin LP, Ding J. Tan WF, et al. Eur J Pharmacol. 2004 Sep 24;499(3):219-28. doi: 10.1016/j.ejphar.2004.07.063. Eur J Pharmacol. 2004. PMID: 15381043
Matrigel plug assays disclosed that pseudolarix acid B reduced angiogenesis induced by VEGF in vivo. In addition, pseudolarix acid B antagonized VEGF-mediated anti-apoptotic effects on serum-deprived human umbilical vein endothelial cells and increased apoptosis of …
Matrigel plug assays disclosed that pseudolarix acid B reduced angiogenesis induced by VEGF in vivo. In addition, pseudolarix …
Pseudolaric acids from Pseudolarix kaempferi.
Zhou BN, Ying BP, Song GQ, Chen ZX, Han J, Yan YF. Zhou BN, et al. Planta Med. 1983 Jan;47(1):35-8. doi: 10.1055/s-2007-969944. Planta Med. 1983. PMID: 17405089
Three novel diterpenoids, pseudolaric acids A, B and C, were isolated from the root bark of Pseudolarix kaempferi Gorden used as an antifungal agent in folk medicine in China. ...
Three novel diterpenoids, pseudolaric acids A, B and C, were isolated from the root bark of Pseudolarix kaempferi Gorden used as an a …
Five new diterpenoids from Pseudolarix kaempferi.
Yang SP, Wu Y, Yue JM. Yang SP, et al. J Nat Prod. 2002 Jul;65(7):1041-4. doi: 10.1021/np0200010. J Nat Prod. 2002. PMID: 12141871
Five new diterpenoids, pseudolaric acids F (1), G (2), and H (3), 2',3'-dihydroxy-1'-propoxypseudolarate B (4), and 6'-O-acetylpseudolaric acid B O-beta-D-glucopyranoside (5), along with nine known diterpenoids, pseudolaric acids A, B, and C(1), deacetylpseudolaric acid C(2), dea …
Five new diterpenoids, pseudolaric acids F (1), G (2), and H (3), 2',3'-dihydroxy-1'-propoxypseudolarate B (4), and 6'-O-acetylpseudolaric a …
Pseudolarix acid B, a new tubulin-binding agent, inhibits angiogenesis by interacting with a novel binding site on tubulin.
Tong YG, Zhang XW, Geng MY, Yue JM, Xin XL, Tian F, Shen X, Tong LJ, Li MH, Zhang C, Li WH, Lin LP, Ding J. Tong YG, et al. Mol Pharmacol. 2006 Apr;69(4):1226-33. doi: 10.1124/mol.105.020537. Epub 2006 Jan 19. Mol Pharmacol. 2006. PMID: 16424078
Tubulin-binding agents have received considerable interest as potential tumor-selective angiogenesis-targeting drugs. Herein, we report that pseudolarix acid B (PAB), isolated from the traditional Chinese medicinal plant Pseudolarix kaempferi Gordon, is a tubulin-bi …
Tubulin-binding agents have received considerable interest as potential tumor-selective angiogenesis-targeting drugs. Herein, we report that …
106 results